CHA collaborative projects bring together peer groups of senior biopharmaceutical managers in a facilitated and pre-competitive forum to evaluate, design, and develop practical solutions to the industry's most pressing R&D challenges. CHA collaborative projects are lead by CHA functional experts who are former operating managers at biopharmaceutical companies and are designed to be completed in less than 12 months. Assessing the Feasibility of Conducting Preclinical Safety Studies in China CHA led a group of seven major biopharmaceutical companies in a project that identified and critically evaluated China-based facilities most capable of performing GLP pre-clinical safety studies. During this six-month project, over forty labs were rigorously assessed and CHA organized and facilitated site visits for the project team at ten selected laboratories. Learn more. Consensus Protocol for Human Sample Collection and Analysis A multi-company collaboration to develop best practice protocols for advanced procedures for human fluid and tissue sample collection and handling and processing for transcriptomic, genomic, proteomic and metabolomic analyses. Learn more. Toxicokinetics (TK) Optimization Multiple companies exploring alternate approaches for evaluating exposure in rat safety studies that do not require the use of satellite TK groups by collecting TK reports from participating companies, and then calculating exposure based on the full data sets, and comparing this to exposure calculated on simulated sparse datasets (i.e. subsets of the original data). Learn more.