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About CHA
Ernie Bush, Ph.D., VP & Scientific Director (formerly F. Hoffman-La Roche)

Vice President & Scientific Director

Dr. Ernie Bush is CHA's leader and expert in the area pre-clinical drug safety.  Ernie serves as Scientific Director on our multi-client, collaborative projects, serving as a liaison and facilitator. 

Ernie has spent over 23 years working in the field of biomedical R&D most of which working in preclinical safety departments for major pharmaceutical companies. From 1992 to 2005 he worked at Hoffmann-La Roche, Inc. and for the last 5 years of that time he led their Non-Clinical Drug Safety Department of 120 members including the functional groups: Drug Metabolism, Non-Clinical Pharmacokinetics, Bioanalytical, Toxicology (including Safety Pharmacology and Teratology), and Pathology. The scope of their responsibilities spanned from early Discovery support through to NDA with particular emphasis on providing an integrated safety assessment to projects across all phases of Discovery and Development.

Ernie has been asked to lead several global initiatives on safety information management practices, including a global safety LIMS system at Roche and a global information repository for toxicogenomics data for the International Life Sciences Institute (ILSI). His in-depth knowledge and broad experience in both the informatics and safety assessment fields has made him a unique leader in today’s complex drug development landscape.

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Direct: 781-320-4018